Company Overview
Integrated Resources Inc. (IRI) is a professional staffing firm specializing in contract, consulting & full time positions in the area of Information Technology, Life Science and Allied Healthcare. Since its inception in 1996, IRI has continued to grow in size, opportunities, service and quality. Our expert team of highly trained counselors work hand in hand with every candidate and client forming a partnership of understanding and commitment.
About the job
Title: Research Associate
Location: Lexington, MA
Duration: 12+ months
TOP 3 MUST HAVE SKILLS:
- Hands-on experience in formulating lipid nanoparticles at small to mid-scale using microfluidics.
- Hands-on experience in characterizing lipid nanoparticles loaded with nucleic acids (e.g. Ribogreen, DLS).
- Hands-on experience in lyophilization of lipid nanoparticles.
Job description:
As a Research Associate in the Nucleic Acid Delivery, Formulations & Bioanalysis department, you will become a part of a multinational and diverse team consisting of fellow Laboratory Technicians, Specialist/Scientists and a global department manager. The goal of the team is to develop synthetic/non-viral nanomedicines, apply advanced analytical characterization techniques and translate these to preclinical and clinical studies through internal and external collaborations.
Essential Functions:
- Regularly formulate and characterize lipid nanoparticles (LNPs) loaded with nucleic acids at small to mid-scale using microfluidics, ensuring reproducibility and scalability of the process while maintaining high product quality and consistency.
- Conduct freeze-drying studies to evaluate the stability of lipid nanoparticles (LNPs). formulations, including assessing critical formulation parameters and optimizing freeze-drying cycles for maximum stability and efficacy of the final product.
- Communicate findings internally to team via presentations and written reports.
- Independent planning, execution, and documentation of experiments.
Qualifications:
- Bachelor’s degree strongly preferred with 2 years’ minimum relevant experience required OR high school diploma with 8+ years’ relevant experience OR Associate or Vocational degree, 4+ years’ relevant experience may also be considered.
Relevant experience can be a combination of industry and academic experience and should include some of the following:
- Hands-on experience in formulating lipid nanoparticles at small to mid-scale using microfluidics
- Experience with analytical methods, this may include biophysical methods like dynamic light scattering (DLS) and fluorescent based assay (e.g. Ribogreen/PicoGreen), chromatography, pH, etc.
- Hands-on experience in lyophilization of lipid nanoparticles.
- Independently operate good lab maintenance and equipment SOPs, etc.
- Experience with automation.